G6PC2 Rabbit Polyclonal Antibody

SKU: BT-AP02763

Size:100μL

Background:This gene encodes an enzyme belonging to the glucose-6-phosphatase catalytic subunit family. These enzymes are part of a multicomponent integral membrane system that catalyzes the hydrolysis of glucose-6-phosphate| the terminal step in gluconeogenic and glycogenolytic pathways| allowing the release of glucose into the bloodstream. The family member encoded by this gene is found in pancreatic islets and does not exhibit phosphohydrolase activity| but it is a major target of cell-mediated autoimmunity in diabetes. Several alternatively spliced transcript variants of this gene have been described| but their biological validity has not been determined.

Research_area:Immunology; Metabolism; Signal transduction

Target_protein:G6PC2

applications:WB

Reactivity:Human, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:G6PC2

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: Q9NQR9; Mouse: Q9Z186

Synonyms:G6PC2; Glucose-6-phosphatase 2; G-6-Pase 2; G6Pase 2; EC 3.1.3.9; Islet-specific glucose-6-phosphatase catalytic subunit-related protein

GeneID:Human: 57818; Mouse: 14378