FXYD4 Rabbit Polyclonal Antibody

SKU: BT-AP10103

Size:100μL

Background:This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain| beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. FXYD4| originally named CHIF for channel-inducing factor| has been shown to modulate the properties of the Na|K-ATPase| as has FXYD2| also known as the gamma subunit of the Na|K-ATPase| and FXYD7. Transmembrane topology has been established for FXYD4 and two family members (FXYD1 and FXYD2)| with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. Alternatively spliced transcript variants encoding the same protein have been found.

Research_area:Signal transduction

Target_protein:FXYD4

applications:IHC-p, IF

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:FXYD4

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):9790

UniProt accession:Human: P59646; Mouse: Q9D2W0; Rat: Q63113

Synonyms:FXYD4

GeneID:Human: 53828; Mouse: 108017; Rat: 64190