FOXA3 Antibody, Biotin conjugated - Cat. #: CSB-PA008796LD01HU

SKU: CSB-PA008796LD01HU

Size :50ug

Clone Number:

Aliases:FKHH3 antibody; Fork head-related protein FKH H3 antibody; forkhead box A3 antibody; Forkhead box protein A3 antibody; Foxa3 antibody; FOXA3_HUMAN antibody; hepatic nuclear factor-3-beta antibody; hepatocyte nuclear factor 3 antibody; hepatocyte nuclear factor 3 gamma antibody; Hepatocyte nuclear factor 3-gamma antibody; HNF-3-gamma antibody; HNF-3G antibody; HNF3B antibody; HNF3G antibody; TCF-3G antibody; TCF3G antibody; Transcription factor 3G antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P55318

Immunogen:Recombinant Human Hepatocyte nuclear factor 3-gamma protein (220-336AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Transcription factor that is thought to act as a \'pioneer\' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites (By similarity). Originally described as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis; binds to and activates transcription from the G6PC promoter. Binds to the CYP3A4 promoter and activates its transcription in cooperation with CEBPA. Binds to the CYP3A7 promoter together with members of the CTF/NF-I family. Involved in regulation of neuronal-specific transcription. May be involved in regulation of spermatogenesis.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Biotin

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:FOXA3

Research Areas:Epigenetics and Nuclear Signaling