FOS Antibody - Cat. #: CSB-PA042478

SKU: CSB-PA042478

Size :100ul

Clone Number:

Aliases:Activator protein 1 antibody; AP 1 antibody; C FOS antibody; Cellular oncogene c fos antibody; Cellular oncogene fos antibody; FBJ murine osteosarcoma viral (v fos) oncogene homolog (oncogene FOS) antibody; FBJ murine osteosarcoma viral oncogene homolog antibody; FBJ murine osteosarcoma viral v fos oncogene homolog antibody; FBJ Osteosarcoma Virus antibody; FOS antibody; FOS protein antibody; FOS_HUMAN antibody; G0 G1 switch regulatory protein 7 antibody; G0/G1 switch regulatory protein 7 antibody; G0S7 antibody; Oncogene FOS antibody; p55 antibody; proto oncogene c Fos antibody; Proto oncogene protein c fos antibody; Proto-oncogene c-Fos antibody; v fos FBJ murine osteosarcoma viral oncogene homolog antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P01100

Immunogen:Peptide sequence around aa.28~32( S-Y-Y-H-S) derived from Human C-Fos.

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB; WB:1:500-1:1000

Background:Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation.

Okazaki K., Sagata N.EMBO J. 14:5048-5059(1995)
Zhang Y., Feng X.H., Derynck R.Nature 394:909-913(1998)
Bossis G., Malnou C.E., Farras R. Mol. Cell. Biol. 25:6964-6979(2005)

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Conjugate:Non-conjugated

Buffer:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:FOS

Research Areas:Epigenetics and Nuclear Signaling?Neuroscience?Cancer