FineTest®700 Anti-Human CD273/PD-L2 Antibody(24F.10C12)

SKU: F700-30133

Size: 20T

Target: Human CD273/PD

Form: liquid

Conjugation: FineTest®700

Conjugation Information: FineTest® 700 is designed to be excited by the Red laser (627-640 nm) and detected using an optical filter centered near 719 nm (e.g., a 725/40 nm bandpass filter).

Purification: 0

Purity: 0

Host: Mouse

Clonality: Monoclonal

Clone ID: 24F.10C12

Isotype: IgG2a, κ

Storage: PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: CD273, known as B7-DC, is also called programmed death ligand 2 (PDL2). This ligand is a 25 kD type I transmembrane protein and a member of B7 family within the immunoglobulin receptor superfamily and is expressed on a subset of dendritic cells, liver and a small subset of macrophages as well as a few transformed cell lines. CD273 has been reported to be stimulatory on dendritic cells when cross-linked and to inhibit T cell activation upon engaging the PD-1 receptor. CD273 has also been reported to bind to an alternative receptor and to mediate T cell activation through such non-PD1 mediated interactions.

Immunogen: 0

Synonyms: B7DC|CD273|PDCD1L2|PDL2

Observed MW:

Uniprot ID: Q9BQ51

Reactivity: Human

Tested Application: FC

Recommended dilution: Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

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Gene ID: 80380

Research Area:

Catagory: Flow cytometry Antibodies