FILA2 Rabbit Polyclonal Antibody

SKU: BT-AP10040

Size:100μL

Background:The filaggrin-like protein encoded by this gene is upregulated by calcium| proteolyzed by calpain 1| and is involved in epithelial homeostasis. The encoded protein is required for proper cornification in skin| with defects in this gene being associated with skin diseases. This protein also has a function in skin barrier protection. In fact| in addition to providing a physical barrier| C-terminal fragments of this protein display antimicrobial activity against P. aeruginosa.

Research_area:Signal transduction

Target_protein:FLG2

applications:WB

Reactivity:Human, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:FILA2

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):263010

UniProt accession:Human: Q5D862; Mouse: Q2VIS4

Synonyms:FILA2

GeneID:Human: 388698; Mouse: 229574