FES Antibody - Cat. #: CSB-PA290275

SKU: CSB-PA290275

Size :100ul

Clone Number:

Aliases:c-fes/fps protein antibody; cFES antibody; Feline sarcoma (Snyder Theilen) viral (v fes)/Fujinami avian sarcoma (PRCII) viral (v fps) oncogene homolog antibody; feline sarcoma (Snyder-Theilen) viral (v-fes)/Fujinami antibody; Feline sarcoma oncogene antibody; Feline sarcoma/Fujinami avian sarcoma oncogene homolog antibody; fes antibody; FES proto oncogene, tyrosine kinase antibody; FES_HUMAN antibody; FPS antibody; Oncogene FES antibody; Oncogene FES feline sarcoma virus antibody; P93c fes antibody; Proto oncogene tyrosine protein kinase Fes/Fps antibody; Proto-oncogene c-Fes antibody; Proto-oncogene c-Fps antibody; proto-oncogene tyrosine-protein kinase Fes/Fps antibody; Tyrosine-protein kinase Fes/Fps antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P07332

Immunogen:Synthesized peptide derived from internal of Human FES.

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB; WB:1:500-1:3000

Background:Tyrosine-protein kinase that acts downstream of cell surface receptors and plays a role in the regulation of the actin cytoskeleton, microtubule assembly, cell attachment and cell spreading. Plays a role in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Acts down-stream of the activated FCER1 receptor and the mast/stem cell growth factor receptor KIT. Plays a role in the regulation of mast cell degranulation. Plays a role in the regulation of cell differentiation and promotes neurite outgrowth in response to NGF signaling. Plays a role in cell scattering and cell migration in response to HGF-induced activation of EZR. Phosphorylates BCR and down-regulates BCR kinase activity. Phosphorylates HCLS1/HS1, PECAM1, STAT3 and TRIM28.

Alcalay M., Oncogene 5:267-275(1990).
Roebroek A.J.M., EMBO J. 4:2897-2903(1985).
Scott A., J. Biomol. NMR 31:357-361(2005).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:FES

Research Areas:Cancer;Signal transduction