FERMT3 antibody , Cat. # FNab03078

SKU: FNab03078

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Plays a central role in cell adhesion in hematopoietic cells(PubMed:19234463, PubMed:26359933). Acts by activating the integrin beta-1-3(ITGB1, ITGB2 and ITGB3)(By similarity). Required for integrin-mediated platelet adhesion and leukocyte adhesion to endothelial cells(PubMed:19234460). Required for activation of integrin beta-2(ITGB2) in polymorphonuclear granulocytes(PMNs)(By similarity). Isoform 2 may act as a repressor of NF-kappa-B and apoptosis.

Immunogen:fermitin family homolog 3(Drosophila)

Synonyms:KIND3, MIG2B, URP2

Observed MW:72-76kd

Uniprot ID:Q86UX7

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, WB, IHC, IF

Recommended dilution:WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

Gene ID:83706

Research Area:Signal Transduction, Immunology