FBXW7 Polyclonal Antibody

SKU: E-AB-11064

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:FBXW7

Target Synonym:AGO;Archipelago;Archipelago homolog;Archipelago;Drosophila;homolog of;CDC4;CDC4;S.cerevisiae;homolog of;DKFZp686F23254;F box and WD 40 domain protein 7 (archipelago homolog;Drosophila);F box and WD 40 domain protein 7;F box and WD repeat domain containing 7;F box protein FBW7;F box protein FBX30;F box protein SEL 10;F box protein SEL10;F-box and WD repeat domain containing 7;E3 ubiquitin protein ligase;F-box and WD-40 domain-containing protein 7;F-box protein FBX30;F-box/WD repeat-containing protein 7;FBW6;FBW7;FBX30;FBXO30;FBXW6;FBXW7;FBXW7;FLJ16457;hAgo;hCdc4;Homolog of C elegans sel 10;Homolog of C.elegans sel10;SEL 10;SEL-10;SEL10

Research Areas:Cancer;Cell Biology

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse

Application:IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:Q969H0

Accession:

Background:This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene was previously referred to as FBX30, and belongs to the Fbws class; in addition to an F-box, this protein contains 7 tandem WD40 repeats.

Concentration:0.3 mg/mL

Immunogen:Recombinant protein of human FBXW7

Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method:Affinity purification

Dilution:IHC 1:100-1:300

Calculated MW:

ObservedMW: