FBXW5 Rabbit Polyclonal Antibody

SKU: BT-AP10013

Size:100μL

Background:This gene encodes a member of the F-box protein family| members of which are characterized by an approximately 40 amino acid motif| the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box)| which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains| Fbls containing leucine-rich repeats| and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains WD-40 domains| in addition to an F-box motif| so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene| however| they were found to be nonsense-mediated mRNA decay (NMD) candidates| hence not represented.

Research_area:Epigenetics and nuclear signaling

Target_protein:FBXW5

applications:WB

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:FBXW5

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: Q969U6; Mouse: Q9QXW2; Rat: Q4KLI9

Synonyms:FBXW5; F-box/WD repeat-containing protein 5; F-box and WD-40 domain-containing protein 5)

GeneID:Human: 54461; Mouse: 30839; Rat: 362081