FBLN5 Antibody - Cat. #: CSB-PA188267

SKU: CSB-PA188267

Size :50ul

Clone Number:

Aliases:ADCL2 antibody; ARCL1A antibody; ARMD3 antibody; Dance antibody; Developmental arteries and neural crest EGF like protein antibody; Developmental arteries and neural crest EGF-like protein antibody; EVEC antibody; Fbln5 antibody; FBLN5_HUMAN antibody; FIBL 5 antibody; FIBL-5 antibody; Fibulin-5 antibody; FLJ90059 antibody; UP50 antibody; Urine p50 protein antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9UBX5

Immunogen:Synthetic peptide of Human FBLN5

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, IHC; ELISA:1:2000-1:10000, IHC:1:50-1:200

Background:The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3).

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:FBLN5

Research Areas:Cardiovascular;Signal transduction