FAT4 Antibody - Cat. #: CSB-PA017577

SKU: CSB-PA017577

Size :50ul

Clone Number:

Aliases:Cadherin family member 14 antibody; Cadherin related family member 11 antibody; CDHF14 antibody; CDHR11 antibody; FAT atypical cadherin 4 antibody; FAT J antibody; FAT tumor suppressor homolog 4 antibody; Fat-like cadherin protein FAT-J antibody; FAT4 antibody; FAT4_HUMAN antibody; FATJ antibody; hFat4 antibody; HKLLS2 antibody; Nbla00548 antibody; Protocadherin Fat 4 antibody; Putative protein product of Nbla00548 antibody; VMLDS2 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q6V0I7

Immunogen:Synthetic peptide of Human FAT4

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:25-1:100

Background:FAT1, FAT2, FAT3 and FAT4 are human homologs of Drosophila Fat, which is involved in tumor suppression and planar cell polarity (PCP). FAT4 undergo the first proteolytic cleavage by Furin and are predicted to undergo the second cleavage by ? secretase to release intracellular domain (ICD). FAT4 directly interacts with MPDZ/MUPP1 to recruit membrane associated guanylate kinase MPP5/PALS1. FAT4 is involved in the maintenance of PCP and inhibition of cell proliferation.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:FAT4

Research Areas:Cancer;Signal transduction