FAT1 Antibody - Cat. #: CSB-PA592424

SKU: CSB-PA592424

Size :50ul

Clone Number:

Aliases:Cadherin family member 7 antibody; Cadherin family member 7 precursor antibody; Cadherin ME5 antibody; Cadherin related tumor suppressor antibody; Cadherin related tumor suppressor homolog antibody; Cadherin related tumor suppressor homolog precursor antibody; Cadherin related tumor suppressor homolog precursor (FAT protein homolog) antibody; Cadherin-related tumor suppressor homolog antibody; CDHF 7 antibody; CDHF7 antibody; FAT 1 antibody; FAT tumor suppressor 1 antibody; FAT tumor suppressor homolog 1 antibody; FAT1 antibody; FAT1_HUMAN antibody; hFat 1 antibody; hFAT antibody; hFat1 antibody; Homolog of Drosophila FAT protein antibody; Homolog of Drosophila FAT protein precursor antibody; Homolog of Drosophila tumor suppressor FAT precursor antibody; ME 5 antibody; ME5 antibody; nuclear form antibody; Protein fat homolog antibody; Protocadherin Fat 1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q14517

Immunogen:Synthetic peptide of Human FAT1

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:50-1:200

Background:This gene is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has five epidermal growth factor (EGF)-like repeats and one laminin A-G domain. This gene is expressed at high levels in a number of fetal epithelia. Its product probably functions as an adhesion molecule and/or signaling receptor, and is likely to be important in developmental processes and cell communication. Transcript variants derived from alternative splicing and/or alternative promoter usage exist, but they have not been fully described.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:FAT1

Research Areas:Epigenetics and Nuclear Signaling;Cancer;Cell biology;Signal transduction