FAS Antibody - Cat. #: CSB-PA146193

SKU: CSB-PA146193

Size :100ul

Clone Number:

Aliases:ALPS 1A antibody; ALPS1A antibody; APO 1 antibody; Apo 1 antigen antibody; APO 1 cell surface antigen antibody; Apo-1 antigen antibody; APO1 antibody; Apo1 antigen antibody; APO1 cell surface antigen antibody; Apoptosis antigen 1 antibody; Apoptosis mediating surface antigen FAS antibody; Apoptosis-mediating surface antigen FAS antibody; APT 1 antibody; APT1 antibody; CD 95 antibody; CD 95 antigen antibody; CD95 antibody; CD95 antigen antibody; Delta Fas antibody; Delta Fas/APO 1/CD95 antibody; Delta Fas/APO1/CD95 antibody; Fas (TNF receptor superfamily; member 6) antibody; FAS 1 antibody; FAS 827dupA antibody; Fas AMA antibody; Fas antibody; FAS Antigen antibody; Fas cell surface death receptor antibody; FAS1 antibody; FASLG receptor antibody; FASTM antibody; sFAS antibody; Surface antigen APO1 antibody; TNF receptor superfamily; member 6 antibody; TNFRSF 6 antibody; TNFRSF6 antibody; TNR6_HUMAN antibody; Tumor necrosis factor receptor superfamily member 6 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P25445

Immunogen:Peptide sequence around aa.323~327 (E-N-S-N-F) derived from Human Fas .

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB; WB:1:500-1:1000

Background:Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).

Hahne, M. et al. (1995) Int Immunol 7, 1381-6.
Nagata, S. (1997) Cell 88, 355-65.
Green, D.R. and Ferguson, T.A. (2001) Nat Rev Mol Cell Biol 2, 917-24.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Conjugate:Non-conjugated

Buffer:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:FAS

Research Areas:Cell biology;Immunology