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GeneBio Systems

Factor XIIIa Polyclonal Antibody

Factor XIIIa Polyclonal Antibody

E-AB-12903

$493.92 CAD
$493.92 CAD
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Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:F13A1

Target Synonym:bA525O21.1 (coagulation factor XIII;A1 polypeptide);Coagulation factor XIII A chain;Coagulation factor XIII A1 polypeptide;Coagulation factor XIII A1 subunit;Coagulation factor XIII;A polypeptide;Coagulation factor XIIIa;F13A;F13A;F13a1;Factor XIIIA;Fibrin stabilizing factor;A subunit;Fibrinoligase;FSF;A subunit;Protein glutamine gamma glutamyltransferase A chain;Protein-glutamine gamma-glutamyltransferase A chain;TGase;Transglutaminase A chain;Transglutaminase;plasma;Transglutaminase. plasma

Research Areas:Cancer;Cardiovascular;Tags and Cell Markers

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P00488

Accession:

Background:This gene encodes the coagulation factor XIII A subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have enzymatic activity and may serve as plasma carrier molecules. Platelet factor XIII is comprised only of 2 A subunits, which are identical to those of plasma origin. Upon cleavage of the activation peptide by thrombin and in the presence of calcium ion, the plasma factor XIII dissociates its B subunits and yields the same active enzyme, factor XIIIa, as platelet factor XIII. This enzyme acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinking between fibrin molecules, thus stabilizing the fibrin clot. It also crosslinks alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin.

Concentration:0.1 mg/mL

Immunogen:Synthetic peptide of human F13A1

Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method:Affinity purification

Dilution:IHC 1:100-1:300

Calculated MW:

ObservedMW:

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