FACR1 Rabbit Polyclonal Antibody

SKU: BT-AP02620

Size:100μL

Background:The protein encoded by this gene is required for the reduction of fatty acids to fatty alcohols| a process that is required for the synthesis of monoesters and ether lipids. NADPH is required as a cofactor in this reaction| and 16-18 carbon saturated and unsaturated fatty acids are the preferred substrate. This is a peroxisomal membrane protein| and studies suggest that the N-terminus contains a large catalytic domain located on the outside of the peroxisome| while the C-terminus is exposed to the matrix of the peroxisome. Studies indicate that the regulation of this protein is dependent on plasmalogen levels. Mutations in this gene have been associated with individuals affected by severe intellectual disability| early-onset epilepsy| microcephaly| congenital cataracts| growth retardation| and spasticity (PMID: 25439727). A pseudogene of this gene is located on chromosome 13.

Research_area:Metabolism

Target_protein:FAR1

applications:WB

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:FACR1

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):56650

UniProt accession:Human: Q8WVX9; Mouse: Q922J9; Rat: Q66H50

Synonyms:FACR1

GeneID:Human: 84188; Mouse: 67420; Rat: 293173