ERO1B Antibody, Biotin conjugated - Cat. #: CSB-PA774834LD01HU

SKU: CSB-PA774834LD01HU

Size :50ug

Clone Number:

Aliases:Endoplasmic oxidoreductin-1-like protein B antibody; Endoplasmic reticulum oxidoreductin-1-like protein B antibody; ERO1; S. cerevisiae; homolog of; beta antibody; ERO1-L-beta antibody; ERO1-like beta (S. cerevisiae) antibody; ERO1-like protein beta antibody; ERO1B_HUMAN antibody; Ero1lb antibody; Oxidoreductin-1-L-beta antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q86YB8

Immunogen:Recombinant Human ERO1-like protein beta protein (101-400AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation. Other protein disulfide isomerase family members can also be reoxidized, but at lower rates compared to P4HB, including PDIA2 (50% of P4HB reoxidation rate), as well as PDIA3, PDIA4, PDIA6 and NXNDC12 (<10%). Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS) in the cell. May be involved in oxidative proinsulin folding in pancreatic cells, hence may play a role in glucose homeostasis.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Biotin

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:ERO1B

Research Areas:Signal transduction