ENTPD5 Antibody - Cat. #: CSB-PA007694ESR2HU

SKU: CSB-PA007694ESR2HU

Size :50ul

Clone Number:

Aliases:CD39 like 4 antibody; AI196558 antibody; AI987697 antibody; CD39 antigen like 4 antibody; CD39 antigen-like 4 antibody; CD39 like 4 antibody; CD39L4 antibody; Ectonucleoside triphosphate diphosphohydrolase 5 antibody; ENTP5_HUMAN antibody; Entpd5 antibody; ER UDPase antibody; ER-UDPase antibody; GDPase ENTPD5 antibody; Guanosine-diphosphatase ENTPD5 antibody; MGC163357 antibody; MGC163359 antibody; mNTPase antibody; NTPDase 5 antibody; Nucleoside diphosphatase antibody; PCPH antibody; Pcph proto oncogene protein antibody; Proto oncogene CPH antibody; UDPase ENTPD5 antibody; Uridine-diphosphatase ENTPD5 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O75356

Immunogen:Recombinant Human Ectonucleoside triphosphate diphosphohydrolase 5 protein (149-428AA)

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB, IHC, IP; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IP:1:200-1:2000

Background:Uridine diphosphatase (UDPase) that promotes protein N-glycosylation and ATP level regulation. UDP hydrolysis promotes protein N-glycosylation and folding in the endoplasmic reticulum, as well as elevated ATP consumption in the cytosol via an ATP hydrolysis cycle. Together with CMPK1 and AK1, constitutes an ATP hydrolysis cycle that converts ATP to AMP and results in a compensatory increase in aerobic glycolysis. The nucleotide hydrolyzing preference is GDP > IDP > UDP, but not any other nucleoside di-, mono- or triphosphates, nor thiamine pyrophosphate. Plays a key role in the AKT1-PTEN signaling pathway by promoting glycolysis in proliferating cells in response to phosphoinositide 3-kinase (PI3K) signaling.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:ENTPD5

Research Areas:Epigenetics and Nuclear Signaling; Cancer; Metabolism; Signal transduction