Eme1 rabbit pAb

SKU: ES4872

Size: 100μL

Source:Rabbit

Applications:WB;ELISA

Reactivity:Human;Rat;Mouse;

Dilution:Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.

Immunogen:Synthesized peptide derived from Eme1 . at AA range: 250-330

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):65kD

Human_gene_id:146956

Human_swiss_prot_no:Q96AY2

Subcellular_location:Nucleus, nucleolus . Recruited to regions of DNA damage in S-phase cells.

Other_name:EME1; MMS4; Crossover junction endonuclease EME1; MMS4 homolog; hMMS4

Background:This gene encodes a protein that complexes with methyl methanesulfonate-sensitive UV-sensitive 81 protein to form an endonuclease complex. The encoded protein interacts with specifc DNA structures including nicked Holliday junctions, 3'-flap structures and aberrant replication fork structures. This protein may be involved in repairing DNA damage and in maintaining genomic stability. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009],