EMD Antibody, FITC conjugated - Cat. #: CSB-PA007633LC01HU

SKU: CSB-PA007633LC01HU

Size :50ug

Clone Number:

Aliases:EDMD antibody; Emd antibody; EMD_HUMAN antibody; Emerin antibody; Emery Dreifuss muscular dystrophy antibody; STA antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P50402

Immunogen:Recombinant Human Emerin protein (1-222AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:

Background:Stabilizes and promotes the formation of a nuclear actin cortical network. Stimulates actin polymerization in vitro by binding and stabilizing the pointed end of growing filaments. Inhibits beta-catenin activity by preventing its accumulation in the nucleus. Acts by influencing the nuclear accumulation of beta-catenin through a CRM1-dependent export pathway. Links centrosomes to the nuclear envelope via a microtubule association. EMD and BAF are cooperative cofactors of HIV-1 infection. Association of EMD with the viral DNA requires the presence of BAF and viral integrase. The association of viral DNA with chromatin requires the presence of BAF and EMD. Required for proper localization of non-farnesylated prelamin-A/C.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:FITC

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:EMD

Research Areas:Signal transduction