ELAC2 Antibody - Cat. #: CSB-PA997561

SKU: CSB-PA997561

Size :50ul

Clone Number:

Aliases:COXPD17 antibody; elaC homolog 2 (E. coli) antibody; ElaC homolog protein 2 antibody; elaC ribonuclease Z 2 antibody; elaC, E. coli, homolog of, 2 antibody; ELAC2 antibody; ELC2 antibody; FLJ10530 antibody; FLJ36693 antibody; FLJ42848 antibody; Heredity prostate cancer protein 2 antibody; HPC2 antibody; putative prostate cancer susceptibility protein HPC2/ELAC2 antibody; Ribonuclease Z 2 antibody; Ribonuclease Z, long form antibody; Ribonuclease Z2 antibody; RNase Z 2 antibody; RNase Z2 antibody; RNase ZL antibody; RNZ2_HUMAN antibody; tRNA 3 endonuclease 2 antibody; tRNase Z (long form) antibody; tRNase Z 2 antibody; tRNase Z2 antibody; Zinc phosphodiesterase ELAC protein 2 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9BQ52

Immunogen:Fusion protein of Human ELAC2

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB, IHC; ELISA:1:2000-1:5000, WB:1:200-1:1000, IHC:1:50-1:200

Background:The protein encoded by this gene has a C-terminal domain with tRNA 3′ processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:ELAC2

Research Areas:Epigenetics and Nuclear Signaling;Cancer