EFNB1 Polyclonal Antibody

SKU: E-AB-53525

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:EFNB1

Target Synonym:CFND;CFNS;Craniofrontonasal syndrome (craniofrontonasal dysplasia);EFL 3;EFL-3;EFL3;EFNB1;EFNB1;Elk L;ELK ligand;ELK-L;Eph related receptor tyrosine kinase ligand 2;EPH-related receptor tyrosine kinase ligand 2;Ephrin-B1;EPLG2;LERK 2;LERK-2;LERK2;Ligand of eph related kinase 2;MGC8782

Research Areas:Cell Biology;Cardiovascular;Developmental Biology;Neuroscience;Signal Transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P98172

Accession:

Background:Ephrin B proteins are thought to play key roles in cellular functions as diverse as neuronal migration and blood vessel development. Ephrin B molecules expressed at the membrane surface bind to the Ephrin B family receptors on target cells during cell to cell contact. This interaction leads to cell signaling in the target cell but also generates a reverse signal in the cell expressing Ephrin B on its surface. This reverse signaling event is thought to be critical for vessel maturation and neuronal development. Importantly, tyrosine phosphorylation of Ephrin B is thought to be a critical component of this reverse signaling event. Recent work demonstrated that Tyr331 of Ephrin B was phosphorylated in HEK293 cells after stimulation by the soluble Ephrin B2 receptor tyrosine kinase.

Concentration:0.9 mg/mL

Immunogen:Synthetic peptide of human EFNB1

Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method:Antigen affinity purification

Dilution:IHC 1:30-1:150

Calculated MW:

ObservedMW: