E2F4 Antibody - Cat. #: CSB-PA00759A0Rb

SKU: CSB-PA00759A0Rb

Size :50ug

Clone Number:

Aliases:E2F 4 antibody; E2F transcription factor 4 antibody; E2F transcription factor 4 p107/p130 binding antibody; E2F-4 antibody; E2F4 antibody; E2F4_HUMAN antibody; p107/p130 binding protein antibody; Transcription factor E2F 4 antibody; Transcription factor E2F4 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q16254

Immunogen:Recombinant Human Transcription factor E2F4 protein (160-299AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200

Background:Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5\\\'-TTTC[CG]CGC-3\\\' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F4 binds with high affinity to RBL1 and RBL2. In some instances can also bind RB1. Specifically required for multiciliate cell differentiation: together with MCIDAS and E2F5, binds and activate genes required for centriole biogenesis.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:E2F4

Research Areas:Epigenetics and Nuclear Signaling; Stem cells