DUSP10 Antibody - Cat. #: CSB-PA929814

SKU: CSB-PA929814

Size :50ul

Clone Number:

Aliases:Dual specificity phosphatase 10 antibody; Dual specificity phosphatase MKP 5 antibody; Dual specificity phosphatase MKP5 antibody; Dual specificity protein phosphatase 10 antibody; DUS10_HUMAN antibody; DUSP 10 antibody; DUSP10 antibody; DUSP10 protein antibody; MAP kinase phosphatase 5 antibody; Mitogen activated protein kinase phosphatase 5 antibody; Mitogen-activated protein kinase phosphatase 5 antibody; MKP 5 antibody; MKP-5 antibody; MKP5 antibody; Serine/threonine specific protein phosphatase antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9Y6W6

Immunogen:Fusion protein of Human DUSP10

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:25-1:100

Background:Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAPK superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of this family of dual specificity phosphatases show distinct substrate specificities for MAPKs, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product binds to and inactivates p38 and SAPK/JNK, but not MAPK/ERK. Its subcellular localization is unique; it is evenly distributed in both the cytoplasm and the nucleus.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:DUSP10

Research Areas:Signal transduction