DTX2 Antibody - Cat. #: CSB-PA803123ESR2HU

SKU: CSB-PA803123ESR2HU

Size :50ul

Clone Number:

Aliases:Deltex 2 antibody; deltex homolog 2 (Drosophila) antibody; deltex; Drosophila; homolog of; 2 antibody; Deltex2 antibody; DTX2 antibody; DTX2_HUMAN antibody; hDTX2 antibody; Highly similar to hPMSR6 [H.sapiens] antibody; KIAA1528 antibody; Probable E3 ubiquitin-protein ligase DTX2 antibody; Protein deltex 2 antibody; Protein deltex-2 antibody; RING finger protein 58 antibody; RNF58 antibody; Zinc ion binding protein antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q86UW9

Immunogen:Recombinant Human Probable E3 ubiquitin-protein ligase DTX2 protein (1-280AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200

Background:Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Functions as a ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:DTX2

Research Areas:Stem cells