DSG3 Monoclonal Antibody

SKU: BT-MCA4276

Size:100μL

Background:Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.

Research_area:Signal transduction

Target_protein:DSG3

applications:WB

Reactivity:Human

Clonality:Monoclonal

Clone ID:6G2E2

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:DSG3

Immunogen:Purified recombinant fragment of human DSG3 (AA: 55-159) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide.

Concentration:

Molecular weight(Da):107.5kDa

UniProt accession:P32926

Synonyms:PVA, CDHF6

GeneID:1830