Dok-2 (phospho Tyr345) rabbit pAb

SKU: ES7940

Size: 100μL

Source:Rabbit

Applications:IHC;IF;ELISA

Reactivity:Human;Mouse

Dilution:Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

Immunogen:Synthesized phospho-peptide around the phosphorylation site of human Dok-2 (phospho Tyr345)

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):

Human_gene_id:9046

Human_swiss_prot_no:O60496

Subcellular_location:cytosol,

Other_name:DOK2; Docking protein 2; Downstream of tyrosine kinase 2; p56(dok-2)

Background:docking protein 2(DOK2) Homo sapiens The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells. [provided by RefSeq, Jul 2008],