DOCK4 Rabbit Polyclonal Antibody

SKU: BT-AP09312

Size:100μL

Background:This gene is a member of the dedicator of cytokinesis (DOCK) family and encodes a protein with a DHR-1 (CZH-1) domain| a DHR-2 (CZH-2) domain and an SH3 domain. This membrane-associated| cytoplasmic protein functions as a guanine nucleotide exchange factor and is involved in regulation of adherens junctions between cells. Mutations in this gene have been associated with ovarian| prostate| glioma| and colorectal cancers. Alternatively spliced variants which encode different protein isoforms have been described| but only one has been fully characterized.

Research_area:Signal transduction

Target_protein:DOCK4

applications:WB

Reactivity:Human, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:DOCK4

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):216260

UniProt accession:Human: Q8N1I0; Mouse: P59764

Synonyms:DOCK4

GeneID:Human: 9732; Mouse: 238130