DLX5 Antibody, HRP conjugated - Cat. #: CSB-PA006956LB01HU

SKU: CSB-PA006956LB01HU

Size :50ug

Clone Number:

Aliases:DLX5Homeobox protein DLX-5 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P56178

Immunogen:Recombinant Human Homeobox protein DLX-5 protein (1-249AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Transcriptional factor involved in bone development. Acts as an immediate early BMP-responsive transcriptional activator essential for osteoblast differentiation. Stimulates ALPL promoter activity in a RUNX2-independent manner during osteoblast differentiation. Stimulates SP7 promoter activity during osteoblast differentiation. Promotes cell proliferation by up-regulating MYC promoter activity. Involved as a positive regulator of both chondrogenesis and chondrocyte hypertrophy in the endochondral skeleton. Binds to the homeodomain-response element of the ALPL and SP7 promoter. Binds to the MYC promoter. Requires the 5\'-TAATTA-3\' consensus sequence for DNA-binding.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:HRP

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:DLX5

Research Areas:Epigenetics and Nuclear Signaling; Neuroscience; Signal transduction; Stem cells