DKK4 Antibody - Cat. #: CSB-PA883367ESR2HU

SKU: CSB-PA883367ESR2HU

Size :50ul

Clone Number:

Aliases:Dickkopf 4 antibody; Dickkopf gene 4 antibody; Dickkopf homolog 4 (Xenopus laevis) antibody; Dickkopf homolog 4 antibody; Dickkopf related protein 4 antibody; Dickkopf-4 antibody; Dickkopf-related protein 4 short form antibody; Dickkopf4 antibody; DKK 4 antibody; Dkk-4 antibody; DKK4 antibody; DKK4_HUMAN antibody; hDkk 4 antibody; hDkk-4 antibody; hDkk4 antibody; MGC129562 antibody; MGC129563 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9UBT3

Immunogen:Recombinant Human Dickkopf-related protein 4 protein (19-224AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200

Background:Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity).

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:DKK4

Research Areas:Stem cells