DIS3L Antibody, Biotin conjugated - Cat. #: CSB-PA823476LD01HU

SKU: CSB-PA823476LD01HU

Size :50ug

Clone Number:

Aliases:DIS3L antibody; DIS3L1 antibody; KIAA1955DIS3-like exonuclease 1 antibody; EC 3.1.13.- antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q8TF46

Immunogen:Recombinant Human DIS3-like exonuclease 1 protein (1-300AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Putative cytoplasm-specific catalytic component of the RNA exosome complex which has 3\'->5\' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3\' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Biotin

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:DIS3L

Research Areas:Epigenetics and Nuclear Signaling; Cell biology