DHCR24 Antibody - Cat. #: CSB-PA237947

SKU: CSB-PA237947

Size :50ul

Clone Number:

Aliases:24 dehydrocholesterol reductase antibody; 24-dehydrocholesterol reductase antibody; 3 beta hydroxysterol delta 24 reductase antibody; 3-beta-hydroxysterol delta-24-reductase antibody; DCE antibody; Delta(24)-sterol reductase antibody; Desmosterol to cholesterol enzyme antibody; DHC24_HUMAN antibody; Dhcr24 antibody; Diminuto dwarf1 homolog antibody; Diminuto/dwarf1 homolog antibody; KIAA0018 antibody; Nbla03646 antibody; Seladin-1 antibody; SELADIN1 antibody; Selective AD indicator 1 antibody; Selective Alzheimer's Disease Indicator 1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q15392

Immunogen:Fusion protein of Human DHCR24

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB, IHC; ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:30-1:150

Background:This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:DHCR24

Research Areas:Neuroscience?Cancer?Cardiovascular?Cell biology;Metabolism