DDIT3 / CHOP Polyclonal Antibody

SKU: E-AB-68246

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:DDIT3 / CHOP

Target Synonym:DDIT3;CEBPZ;CHOP;CHOP-10;CHOP10;GADD153;C/EBPzeta;DDIT3 / CHOP

Research Areas:Cancer;Epigenetics and Nuclear Signaling;Metabolism;Developmental Biology;Stem Cells

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB;IF

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P35638

Accession:

Background:This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified.

Concentration:1 mg/mL

Immunogen:A synthetic peptide of human DDIT3 / CHOP

Buffer:PBS with 0.05% proclin300,50% glycerol,pH7.3.

Purification method:Affinity purification

Dilution:WB 1:500-1:2000;IF 1:50-1:200

Calculated MW:19kDa/21kDa

ObservedMW:27KDa