DDC Polyclonal Antibody

SKU: E-AB-19409

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: DDC

Target Synonym: AADC;Aromatic L Amino Acid Decarboxylase;Aromatic-L-amino-acid decarboxylase;DDC;DDC_HUMAN;DOPA decarboxylase (aromatic L-amino acid decarboxylase);DOPA decarboxylase

Research Areas: Neuroscience;Cancer;Metabolism

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human

Application: WB;IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P20711

Accession:

Background: The encoded protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Concentration: 1.5 mg/mL

Immunogen: Synthetic peptide of human DDC

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: WB 1:500-1:2000;IHC 1:25-1:100

Calculated MW: 54 kDa

ObservedMW: Refer to figures