DCTN3 Polyclonal Antibody

SKU: E-AB-11144

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:DCTN3

Target Synonym:DCNT22;DCTN 22;DCTN22;Dctn3;DCTN3;dynactin 3 (p22);dynactin 3;dynactin 3 isoform 1;Dynactin complex subunit 22 kDa subunit;dynactin light chain;Dynactin subunit 3;p22

Research Areas:Cancer;Cell Biology;Signal Transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human

Application:IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:O75935

Accession:

Background:This gene encodes the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, cytokinesis, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like most other dynactin subunits, exists only as a part of the dynactin complex. It is primarily an alpha-helical protein with very little coiled coil, and binds directly to the largest subunit (p150) of dynactin. Alternative splicing results in multiple transcript variants.

Concentration:0.6 mg/mL

Immunogen:Recombinant protein of human DCTN3

Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method:Affinity purification

Dilution:IHC 1:100-1:300

Calculated MW:

ObservedMW: