DAPK1 (Phospho-Ser308) rabbit pAb

SKU: ES17023

Size: 100μL

Source:Rabbit

Applications:IHC;IF;WB

Reactivity:Human; Mouse

Dilution:IHC-p 1:50-200, WB 1:500-2000

Immunogen:Synthesized peptide derived from human DAPK1 (Phospho-Ser308)

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):160kD

Human_gene_id:1612

Human_swiss_prot_no:P53355

Subcellular_location:[Isoform 1]: Cytoplasm. Cytoplasm, cytoskeleton. Colocalizes with MAP1B in the microtubules and cortical actin fibers.; [Isoform 2]: Cytoplasm. Cytoplasm, cytoskeleton.

Other_name:Death-associated protein kinase 1 (DAP kinase 1;EC 2.7.11.1)

Background:Death-associated protein kinase 1 is a positive mediator of gamma-interferon induced programmed cell death. DAPK1 encodes a structurally unique 160-kD calmodulin dependent serine-threonine kinase that carries 8 ankyrin repeats and 2 putative P-loop consensus sites. It is a tumor suppressor candidate. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013],