Dab1(Phospho-Tyr220) Rabbit Polyclonal Antibody

SKU: BT-AP08878

Size:100μL

Background:The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice| the disabled-1 gene plays a central role in brain development| directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1| and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. Alternatively spliced transcript variants of this gene have been reported| but their full length nature has not been determined.

Research_area:Neuroscience; Signal transduction

Target_protein:DAB1

applications:WB

Reactivity:Human, Rat, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Dab1

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: O75553; Mouse: P97318; Rat: Q8CJH2

Synonyms:Dab1 ;Tyr220; Disabled homolog 1

GeneID:Human: 1600; Mouse: 13131; Rat: 266729