Cytokeratin 18 Mouse mAb

SKU: EM1095

Size: 100μL

Source:Mouse

Applications:WB, IHC, IF

Reactivity:Human, Rat, Mouse

Dilution:WB 1:1,000-3,000 IF 1:100-200 IHC 1:200-500

Immunogen:Recombinant Protein

Storage_stability:PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Clonality:Monoclonal

Isotype:IgG1

Concentration:1mg/mL

Observed_band(KD):46kDa

Human_gene_id:3875

Human_swiss_prot_no:P05783

Subcellular_location:Cytoplasm, Intermediate filament, Keratin, Nucleus

Other_name:Cell proliferation inducing gene 46 protein, CK 18, CYK 18, K 18, Keratin 18, Ketatin D, KRT18

Background:Keratin 18 is a type I cytokeratin. It is, together with its filament partner keratin 8, perhaps the most commonly found products of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.Keratin 18 is often used together with keratin 8 and keratin 19 to differentiate cells of epithelial origin from hematopoietic cells in tests that enumerate circulating tumor cells in blood.