CYP24A1 Antibody - Cat. #: CSB-PA221533

SKU: CSB-PA221533

Size :100ul

Clone Number:

Aliases:1 25 @dihydroxyvitamin D3 24 hydroxylase antibody; 1 25 dihydroxyvitamin D(3) 24 hydroxylase antibody; 1 antibody; 1,25-dihydroxyvitamin D(3) 24-hydroxylase; mitochondrial antibody; 24 OHase antibody; 24-OHase antibody; 25-dihydroxyvitamin D(3) 24-hydroxylase antibody; CP 24 antibody; CP24 antibody; CP24A_HUMAN antibody; CYP 24 antibody; CYP24 antibody; CYP24A1 antibody; Cytochrome P450 24A1 antibody; Cytochrome P450 24A1 mitochondrial antibody; cytochrome P450 CC24 antibody; Cytochrome P450 family 24 antibody; Cytochrome P450 family 24 subfamily A member 1 antibody; Cytochrome P450 family 24 subfamily A polypeptide 1 antibody; Cytochrome P450 subfamily XXIV antibody; Cytochrome P450; subfamily XXIV (vitamin D 24-hydroxylase) antibody; Cytochrome P450-CC24 antibody; EC 1.14.13.n4 antibody; Exo mitochondrial protein antibody; HCAI antibody; HCINF1 antibody; MGC126273 antibody; MGC126274 antibody; mitochondrial antibody; P450 CC24 antibody; Vitamin D 24 hydroxylase antibody; Vitamin D(3) 24 hydroxylase antibody; Vitamin D(3) 24-hydroxylase antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q07973

Immunogen:Synthesized peptide derived from internal of Human Cytochrome P450 24A1.

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB; WB:1:500-1:3000

Background:Has a role in maintaining calcium homeostasis. Catalyzes the NADPH-dependent 24-hydroxylation of calcidiol (25-hydroxyvitamin D3) and calcitriol (1-alpha,25-dihydroxyvitamin D3). The enzyme can perform up to 6 rounds of hydroxylation of calcitriol leading to calcitroic acid. It also shows 23-hydroxylating activity leading to 1-alpha,25-dihydroxyvitamin D(3)-26,23-lactone as end product.

Chen K.-S., Proc. Natl. Acad. Sci. U.S.A. 90:4543-4547(1993).
Deloukas P., Nature 414:865-871(2001).
Chen K.-S., Biochim. Biophys. Acta 1263:1-9(1995).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:CYP24A1

Research Areas:Cancer?Cardiovascular;Metabolism;Signal transduction