CUX1 Antibody - Cat. #: CSB-PA273037

SKU: CSB-PA273037

Size :100ul

Clone Number:

Aliases:CUX1 antibody; CUTL1Homeobox protein cut-like 1 antibody; CCAAT displacement protein antibody; CDP antibody; Homeobox protein cux-1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P39880

Immunogen:Synthesized peptide derived from N-terminal of Human CUTL1.

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB; WB:1:500-1:3000

Background:Probably has a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor; binds to the matrix attachment regions (MARs) (5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Binds to the TH enhancer; may require the basic helix-loop-helix protein TCF4 as a coactivator By similarity.

Neufeld E.J., Nat. Genet. 1:50-55(1992).
Gloeckner G., Genome Res. 8:1060-1073(1998).
Rong Zeng W., Gene 241:75-85(2000).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:CUX1

Research Areas:Epigenetics and Nuclear Signaling