CUEDC2 Antibody - Cat. #: CSB-PA140363

SKU: CSB-PA140363

Size :100ul

Clone Number:

Aliases:bA18I14.5 antibody; C10orf66 antibody; Chromosome 10 open reading frame 66 antibody; CUE domain containing 2 antibody; CUE domain-containing protein 2 antibody; CUED2 antibody; CUED2_HUMAN antibody; Cuedc2 antibody; MGC2491 antibody; OTTHUMP00000020368 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9H467

Immunogen:Peptide sequence around aa.262~266(D-V-R-N-P) derived from Human CUEDC2.

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB; WB:1:500-1:1000

Background:

Down-regulates ESR1 protein levels through the ubiquitination-proteasome pathway, regardless of the presence of 17 beta-estradiol. Also involved in 17 beta-estradiol-induced ESR1 degradation. Controls PGR protein levels through a similar mechanism.

Zhang P.-J., Zhao J., Li H.-Y. EMBO J. 26:1831-1842(2007)

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Conjugate:Non-conjugated

Buffer:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:CUEDC2

Research Areas:Epigenetics and Nuclear Signaling;Signal transduction