CTSC Antibody - Cat. #: CSB-PA358929

SKU: CSB-PA358929

Size :50ul

Clone Number:

Aliases:AI047818 antibody; CATC antibody; CATC_HUMAN antibody; Cathepsin C antibody; Cathepsin J antibody; CPPI antibody; CTSC antibody; Dipeptidyl peptidase 1 antibody; Dipeptidyl peptidase 1 light chain antibody; Dipeptidyl peptidase I antibody; Dipeptidyl peptidase I exclusion domain chain antibody; Dipeptidyl peptidase I heavy chain antibody; Dipeptidyl peptidase I light chain antibody; Dipeptidyl transferase antibody; DPP I antibody; DPP-I antibody; DPPI antibody; EC 3.4.14.1 antibody; HMS antibody; JP antibody; JPD antibody; MGC126959 antibody; PALS antibody; PDON1 antibody; PLS antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P53634

Immunogen:Synthetic peptide of Human CTSC

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB, IHC; ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:15-1:50

Background:The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor, and a residual portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:CTSC

Research Areas:Cell biology;Tags & Cell Markers