CTNNA1 Polyclonal Antibody

SKU: E-AB-10207

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:CTNNA1

Target Synonym:Alpha E-catenin;Cadherin associated protein 102kDa;Cadherin associated protein;Cadherin-associated protein;CAP 102;CAP102;Catenin (cadherin associated protein) alpha 1 102kDa;Catenin (cadherin associated protein);alpha 1;102kDa;Catenin alpha 1;Catenin alpha-1;CTNA1;CTNNA 1;Ctnna1;FLJ36832;FLJ52416;MDPT2;NY REN 13 antigen;OTTHUMP00000224141;OTTHUMP00000224147;Renal carcinoma antigen NY REN 13;Renal carcinoma antigen NY-REN-13

Research Areas:Cancer;Signal Transduction;Stem Cells

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse

Application:WB;IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P35221

Accession:

Background:Catenin alpha-1is aproteinthat in humans is encoded by theCTNNA1gene. Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Can associate with both E- and N-cadherins. Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions. In contrast, cortical actin was found to be mucHuman, Mouseore dynamic than E-cadherin/catenin complexes and CTNNA1 was shown not to bind to F-actin when assembled in the complex suggesting a different linkage between actin and adherens junctions components.

Concentration:0.2 mg/mL

Immunogen:Recombinant protein of human CTNNA1

Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method:Affinity purification

Dilution:WB 1:500-1:2000;IHC 1:50-1:200

Calculated MW:100kDa

ObservedMW: