CTLA4 Antibody - Cat. #: CSB-PA224600

SKU: CSB-PA224600

Size :100ul

Clone Number:

Aliases:ALPS5 antibody; CD 152 antibody; CD antibody; CD152 antibody; CD152 antigen antibody; CD152 isoform antibody; Celiac disease 3 antibody; CELIAC3 antibody; CTLA 4 antibody; CTLA-4 antibody; CTLA4 antibody; CTLA4_HUMAN antibody; Cytotoxic T cell associated 4 antibody; Cytotoxic T lymphocyte antigen 4 antibody; Cytotoxic T lymphocyte associated 4 antibody; Cytotoxic T lymphocyte associated 4, soluble isoform, included antibody; Cytotoxic T lymphocyte associated antigen 4 antibody; Cytotoxic T lymphocyte associated antigen 4 short spliced form antibody; Cytotoxic T lymphocyte associated protein 4 antibody; Cytotoxic T lymphocyte associated serine esterase 4 antibody; Cytotoxic T lymphocyte protein 4 antibody; Cytotoxic T-lymphocyte protein 4 antibody; Cytotoxic T-lymphocyte-associated antigen 4 antibody; GRD4 antibody; GSE antibody; ICOS antibody; IDDM12 antibody; insulin-dependent diabetes mellitus 12 antibody; Ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4 antibody; OTTHUMP00000216623 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P16410

Immunogen:Synthetic peptide corresponding to residues near the C terminal of Human Cytotoxic T-lymphocyte protein 4

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, IHC; IHC:1:50-1:100

Background:This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:CTLA4

Research Areas:Immunology;Stem cells