COPS5 Polyclonal Antibody

SKU: E-AB-10415

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: COPS5

Target Synonym: 38 kDa Mov34 homolog;COP9 (constitutive photomorphogenic) homolog subunit 5;COP9 constitutive photomorphogenic homolog subunit 5;COP9 signalosome complex subunit 5;COP9 signalosome subunit 5;Cop9 subunit 5;COPS 5;cops5;CSN 5;CSN5;CSN5;JAB 1;Jun activation domain binding protein 1;Jun activation domain binding protein;Jun activation domain-binding protein 1;MGC3149;MOV 34;MOV34;MOV34 family;38-KD member;SGN 5;SGN5;Signalosome subunit 5

Research Areas: Cancer;Cell Biology;Epigenetics and Nuclear Signaling;Neuroscience;Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse

Application: WB;IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q92905

Accession:

Background: The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors

Concentration: 0.9 mg/mL

Immunogen: Recombinant protein of human COPS5

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: WB 1:1000-1:5000;IHC 1:150-1:500

Calculated MW: 38kDa

ObservedMW: