COL17A1 Polyclonal Antibody

SKU: E-AB-19718

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: COL17A1

Target Synonym: 180 kDa bullous pemphigoid antigen 2;Alpha 1 type XVII collagen;BA16H23.2;BP 180;BP180;BPA 2;BPAG 2;BPAG2;Bullous pemphigoid antigen 2;COL17A1;Collagen 17;Collagen alpha 1 XVII chain;Collagen alpha 1(XVII) chain;Collagen alpha1 XVII chain;Collagen type XVII alpha 1;Collagen XVII alpha 1 polypeptide;CollagenXVII;Epidermolysis bullosa junctional localisata variant;FLJ60881;KIAA0204;LAD 1;LAD1

Research Areas: Cancer;Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse

Application: IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q9UMD9

Accession:

Background: COL17A1 (Collagen Type XVII Alpha 1 Chain) is a Protein Coding gene. Diseases associated with COL17A1 include Epidermolysis Bullosa, Junctional, Non-Herlitz Type and Epithelial Recurrent Erosion Dystrophy. Among its related pathways are Collagen chain trimerization and Phospholipase-C Pathway. An important paralog of this gene is COL6A1.This gene encodes the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in this gene are associated with both generalized atrophic benign and junctional epidermolysis bullosa. Two homotrimeric forms of type XVII collagen exist. The full length form is the transmembrane protein. A soluble form, referred to as either ectodomain or LAD-1, is generated by proteolytic processing of the full length form.

Concentration: 1.38 mg/mL

Immunogen: Synthetic peptide of human COL17A1

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: IHC 1:50-1:200

Calculated MW:

ObservedMW: