CNOT2 antibody , Cat. # FNab01807

SKU: FNab01807

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Required for the CCR4-NOT complex structural integrity. Can repress transcription and may link the CCR4-NOT complex to transcriptional regulation; the repressive function may specificly involve the N-Cor repressor complex containing HDAC3, NCOR1 and NCOR2. Involved in the maintenance of emryonic stem(ES) cell identity.

Immunogen:CCR4-NOT transcription complex, subunit 2

Synonyms:CDC36, NOT2

Observed MW:60 kDa

Uniprot ID:Q9NZN8

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, WB

Recommended dilution:WB: 1:500-1:2000

Gene ID:4848

Research Area:Epigenetics, Metabolism