CK1 Monoclonal Antibody

SKU: BT-MCA4006

Size:100μL

Background:CK1 (also designated Cytokeratin 1 or KRT1 ),with 644-amino acid protein (about 70kDa), is a member of the keratin family. Cytokeratins play a critical role in differentiation and tissue specialization, and they function to maintain the overall structural integrity of epithelial cells.CK1 consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. CK1 is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma.

Research_area:Others

Target_protein:CK1

applications:IHC

Reactivity:Human

Clonality:Monoclonal

Clone ID:3C10F7

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:CK1

Immunogen:Purified recombinant fragment of CK1 expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):

UniProt accession:P04264

Synonyms:K1, CK1, EHK, EHK1, EPPK, KRT1A, NEPPK

GeneID:3848