CHRNA7 Antibody - Cat. #: CSB-PA969473

SKU: CSB-PA969473

Size :50ul

Clone Number:

Aliases:7nAChR antibody; a7 nicotinic acetylcholine receptor antibody; acetylcholine receptor; neuronal nicotinic; alpha-7 subunit antibody; ACHA7_HUMAN antibody; AChR antibody; Acra7 antibody; alpha 7 neuronal nicotinic acetylcholine receptor antibody; alpha-7 nicotinic cholinergic receptor subunit antibody; alpha7 antibody; cholinergic receptor; neuronal nicotinic; alpha polypeptide 7 antibody; cholinergic receptor; nicotinic; alpha 7 (neuronal) antibody; cholinergic receptor; nicotinic; alpha 7 antibody; cholinergic receptor; nicotinic; alpha polypeptide 7 antibody; CHRNA7 antibody; CHRNA7-2 antibody; NACHRA7 antibody; neuronal acetylcholine receptor protein; alpha-7 chain antibody; Neuronal acetylcholine receptor subunit alpha-7 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P36544

Immunogen:Synthetic peptide of Human CHRFAM7A

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB, IHC; ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100

Background:The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The family member CHRNA7, which is located on chromosome 15 in a region associated with several neuropsychiatric disorders, is partially duplicated and forms a hybrid with a novel gene from the family with sequence similarity 7 (FAM7A). Alternative splicing has been observed, and two variants exist, for this hybrid gene. The N-terminally truncated products predicted by the largest open reading frames for each variant would lack the majority of the neurotransmitter-gated ion-channel ligand binding domain but retain the transmembrane region that forms the ion channel. Although current evidence supports transcription of this hybrid gene, translation of the nicotinic acetylcholine receptor-like protein-encoding open reading frames has not been confirmed.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:CHRNA7

Research Areas:Others