CHMP5 Antibody, HRP conjugated - Cat. #: CSB-PA878944LB01HU

SKU: CSB-PA878944LB01HU

Size :50ug

Clone Number:

Aliases:apoptosis-related protein PNAS-2 antibody; C9orf83 antibody; CGI 34 antibody; Charged multivesicular body protein 5 antibody; CHMP 5 antibody; CHMP family; member 5 antibody; chmp5 antibody; CHMP5_HUMAN antibody; Chromatin modifying protein 5 antibody; Chromatin-modifying protein 5 antibody; Chromosome 9 open reading frame 83 antibody; HGNC:26942 antibody; HSPC177 antibody; hVps60 antibody; PNAS 2 antibody; SNF7 domain containing protein 2 antibody; SNF7 domain-containing protein 2 antibody; SNF7DC2 antibody; Vacuolar protein sorting 60 antibody; Vacuolar protein sorting-associated protein 60 antibody; Vps60 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9NZZ3

Immunogen:Recombinant Human Charged multivesicular body protein 5 protein (1-219AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. Involved in HIV-1 p6- and p9-dependent virus release.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:HRP

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:CHMP5

Research Areas:Signal transduction